AHCC 섭취가 일회성 운동 시 혈중 C-반응성 단백질 및 활성 산소 유리기, 총항산화능에 미치는 영향

초록

This study was to investigate the effects of AHCC supplementation on plasma CRP, free oxygen radicals, total antioxidant capacity after acute aerobic exercise. Twenty-one healthy male subjects participated in this study. They are divided into three groups; AHCC group(750mg/day), vitamin group(vitamin C 1000mg/day + vitamin E 400IU/day) and placebo group, and supplemented for 4 weeks. All subjects underwent running exercise on a treadmill for 30 minutes at a work load corresponding to 80% of HRmax at before and after treatment. Blood was sampled from a forearm vein at rest, immediately postexercise, and 30min, 24hr after exercise. These samples were analyzed for plasma CRP content, free oxygen radicals, and total antioxidant capacity. There was a significant increase in plasma CRP content, free oxygen radicals, and total antioxidant capacity after exercise and all of which were recovered at 24hr after exercise in three groups. Supplementation of AHCC significantly decreased CRP content and free oxygen radicals, and increased total antioxidant capacity after exercise compared with placebo group. Vitamins supplementation showed the same or better effects than AHCC treatment. These anti-inflammatory and anti-oxidant effects expressed, too, at resting level of CRP and total antioxidant capacity. These results suggested that AHCC supplementation significantly reduced the plasma CRP level and free oxygen radicals, and significantly improved antioxidant capacity after acute exercise, even though these effects were not more than vitamins treatment.

키워드