Alkenylation of Phosphacoumarins via Aerobic Oxidative Heck Reactions and Their Synthetic Application to Fluorescent Benzophosphacoumarins

Kim, Cheol-Eui; Son, Jeong-Yu; Shin, Seohyun; Seo, Boram; Lee, Phil Ho

doi:10.1021/acs.orglett.5b00020

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Alkenylation of Phosphacoumarins via Aerobic Oxidative Heck Reactions and Their Synthetic Application to Fluorescent Benzophosphacoumarins

Kim, Cheol-Eui;
Son, Jeong-Yu;
Shin, Seohyun;
Seo, Boram;
Lee, Phil Ho

Citations

WEB OF SCIENCE

40

Citations

SCOPUS

44

초록

Alkenylation of phosphacoumarins is developed from the reaction of phosphacoumarins with a variety of activated as well as nonactivated alkenes via aerobic oxidative Heck reactions. In addition, 3-alkenylphosphacoumarins undergo an inverse electron demand Diels-Alder reaction (IEDDA) with enamines in situ generated from ketone and pyrrolidine followed by 1,2-elimination and a dehydrogenation, producing fluorescent benzophosphacoumarins.

키워드

CATALYZED OLEFINATION; H FUNCTIONALIZATION; EFFICIENT ROUTE; CYCLIZATION; PHOSPHAISOCOUMARINS; PHOSPHORUS; ACTIVATION; ANNULATION; OXIDES; HETEROCYCLES

제목: Alkenylation of Phosphacoumarins via Aerobic Oxidative Heck Reactions and Their Synthetic Application to Fluorescent Benzophosphacoumarins

저자: Kim, Cheol-Eui; Son, Jeong-Yu; Shin, Seohyun; Seo, Boram; Lee, Phil Ho

DOI: 10.1021/acs.orglett.5b00020

발행일: 2015-02-20

유형: Article

저널명: Organic Letters

권: 17

호: 4

페이지: 908 ~ 911