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초록
Immune enhancing activities of water and ethanol extracts of Hypericum perforatum L. (HP) were examined. HP extracts inhibited the growth of human hepatocarcinoma, human gastric cancer cell and human breast cnacer cells in concentration-dependent mammers over a concentration range of 0.05~1.0㎎/㎖, showing inhibiton of more than 80% with the concentration of 1.0㎎/㎖. However, HP the same concentration. Overall selectivity of the extracts on the three human cancer lines was over 3.5, which is higher than those from the conventional herbs. The growth of human immune B and T cells was enhanced up after 6 days incubation increased the secretions of tumor necrosis factor-alpha (TNF-α )from T cells and interleukin-6 (IL-6) from B cells to 6.7pg/cell and 6.8 /cell, respectively. These results suggest that HP has a potent immune enhancing effect.
키워드
- 제목
- 고추나물의 면역 활성
- 제목 (타언어)
- Immune Activities in Hypericum perforatum L.
- 저자
- 박진홍; 김대호; 이현용; 최근표; 류이하; 이강윤
- 발행일
- 2004-09
- 유형
- Y
- 저널명
- 한국약용작물학회지
- 권
- 12
- 호
- 4
- 페이지
- 304 ~ 308