Iron(III)-Catalyzed Conia-Ene Cyclization of 2-Alkynic 1,3-Dicarbonyl Compounds

  • Chan, Li Yan
  • Kim, Sunggak
  • Park, Youngchul
  • Lee, Phil Ho
Citations

WEB OF SCIENCE

50
Citations

SCOPUS

47

초록

A cheap, simple, and effective FeCl3-catalyzed Conia-ene cyclization of 2-alkynic 1,3-dicarbonyl compounds was stereospecific to afford alkylidenecyclopentanes in (E)-isomers via the 5-exo-dig pathway. The 5-endo-dig and 6-exo-dig cyclizations were also possible, depending on the structure of the substrates.

키워드

ONE-POT SYNTHESISCOOPERATIVE CATALYSISBETA-KETOESTERSEFFICIENTIRONETHENETRICARBOXYLATESCYCLOISOMERIZATIONCONSTRUCTIONALCOHOLSLIGANDS
제목
Iron(III)-Catalyzed Conia-Ene Cyclization of 2-Alkynic 1,3-Dicarbonyl Compounds
저자
Chan, Li YanKim, SunggakPark, YoungchulLee, Phil Ho
DOI
10.1021/jo300957q
발행일
2012-06-15
유형
Article
저널명
The Journal of Organic Chemistry
77
12
페이지
5239 ~ 5244