연근별 황기의 항산화 및 항당뇨 활성 평가 고찰

초록

The antioxidant and anti-diabetes effects were evaluated by the ethanol extracts from Astragalus membranaceus root classified by years using through DPPH radical scavenging activity, hydroxyl radical ( ·OH) scavenging activity, total phenolic and flavonoid contents, reducing power activity, α-amylase and α-glucosidase inhibitory activities. IC50 values for DPPH radical scavenging activity of ethanol extract from 6 years old root (749.25 µg/mL) was higher than 1 year (1452.67 µg/mL) and 3 years old root (1095.61 µg/mL). 6 years old root showed better effects in ·OH scavenging activity (IC50: 10.58 µg/mL), reducing power, total phenolic contents (26.13±0.79 Tan µg/mg, 24.03±0.74 Cat µg/mg) α-amylase (33.33±0.55%) and α-glucosidase inhibitory activity (49.71±1.01%). On the other hand, total flavonoid compound contents were estimated much higher in 1 year old root (44.93±1.35 Que µg/mg, 70.32±2.03 Rut µg/mg) than others. Based on these results, It was suggested that 6 years old root of A. membranaceus has a potential candidate for functional cosmetic and medicine.

키워드