Nanogels Composed of Cinnamoyl Alginate and Cinnamoyl Pluronic F127

초록

Temperature-responsive nanogels were developed by photo crosslinking cinnamoyl alginate (CinAlg) and cinnamoyl Pluronic F127 (CinPlu). On the H-1 NMR spectrum of CinAlg, one molecule of cinnamoyl group was calculated to be attached to every 7.7 units of the pyranose of alginate. On the H-1 NMR spectrum of CinPlu, the molar ratio of Pluronic F127 to cinnamoyl group was calculated to be about 1:1.1. The air/water interfacial tension of CinAlg/CinPlu mixture solution was much lower than that of CinPlu solution and that of CinAlg solution, possibly due to their hydrophobic complexation. The nanogels were sphere-like particles on TEM photos. The mean diameter of the nanogel, determined by a dynamic light scattering technique, increased from 106nm to 177nm at room temperature when a UV light (365nm, 400W) was irradiated to the suspension for 60 minutes, possibly due to interparticle crosslinkage. It decreased with increasing temperature possibly because of the heat-induced condensation of Pluronic F127 chains. The absolute value of the negative zeta potential decreased with increasing the irradiation time, possibly due to the photo-induced condensation of alginate chains. And, it increased with increasing the temperature possibly due to the heat-induced condensation of Pluronic F127 chains. [GRAPHICS]

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